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Research Article

Academia Journal of Biotechnology 7(9): 148-151, September 2019
DOI: 10.15413/ajb.2019.0113
ISSN: 2315-7747
2019 Academia Publishing

Abstract


Theoretical analysis indicates human genome is not a blueprint of life, but a storage of genes and human oocytes have an instruction
 

Accepted 28th August, 2019
 
Mariko Itoh, Kenichi Itoh and Koichi Itoh*

The Institute for Theoretical Molecular Biology, 21-13, Rokurokuso-cho, Ashiya, Hyogo, Japan 659-0011.


Is Human Genome really a blueprint of life? If it is not a blueprint, how are human bodies constructed? Firstly, the present study solves this proposition. We indicate 9 examples of important biological pathways and factors among house-keeping gene products and proved that human genome is not a blueprint of life. Loci of genes in biological pathways of 9 examples are scattered at random in Human Genome in one-dimension. If the Human Genome is the blueprint, 9 important exceptions are not acceptable. That is why Human Genome is not a blueprint of life but a storage of genes. Secondly, we proved that human oocytes have an instruction for development and differentiation. In this case, we used opened public database NCBI for expression profiles of human oocytes. We discovered about 22,000 genes which are all gene expressed in human oocytes. This indicates that human oocytes have the instruction for human body planning. Here we show that human genome is not a blueprint of life but a storage of genes, and human oocytes have the instructions.

Key words: Human genome, blueprint, oocytes.

 

This is an open access article published under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Cite this article as:
Mariko I, Kenichi I, Koichi I (2019). Theoretical analysis indicates human genome is not a blueprint of life, but a storage of genes and human oocytes have an instruction. Acad. J. Biotechnol. 7(9): 148-151

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