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Research Article

Academia Journal of Biotechnology 9(2): 038-045, February 2021
DOI: 10.15413/ajb.2021.0103
ISSN 2315-7747
2021 Academia Publishing



Comparative clinical and neuropsychological characteristics in schizophrenia and schizophrenia-obsessive compulsive disorder patients

Accepted 18th February, 2021

Zekeriya Temircan1,2

1Department of Health/Clinic Psychology and Neuropsychology of Erciyes University, Kayseri, Turkey.
2Mehmet Akif Ersoy Caddesi, Talas, Kayseri, TR 38030.

This study aimed to determine schizophrenia patients accompanied by Obsessive Compulsive Disorder (OCD), schizophrenia patients not accompanied by OCD in terms of socio-demographic, clinical and neuropsychological characteristics. A total of 73 patients aged 18-65 years were included and 29 patients followed up with a diagnosis of schizophrenia according to DSM-IV, alongside 44 patients with a diagnosis of schizophrenia-OCD. Patients diagnosed with schizophrenia and diagnosed with schizophrenia and OCD (Y-BOCS ≥8) based on DSM-IV diagnostic criteria. The inclusion criteria was; patients who have been stable in terms of clinical condition and treatment for at least 3 months. Patients without a history of head trauma, neurological disease, mental retardation, alcohol and substance use disorder, and serious general medical disease. In this study, it was found that schizophrenia-OCD association was seen at a higher rate in male patients, and the schizophrenia-OCD group had some worse clinical features (more severe negative, positive and general psychopathology symptoms, more susceptibility to extrapyramidal side effects, more severe disease, higher numbers and doses of antipsychotics and additional medication) and poorer quality of life. There was no significant difference between the two groups in terms of all other socio-demographic characteristics, characteristics of the disease, clinical characteristics, and social and neuropsychological functionality. The findings of the study showed that schizophrenia-OCD might be comorbidity or a sub-type of schizophrenia, which does not have severe clinical or neuropsychological symptoms. However, schizophrenia-OCD patients experience more depression and anxiety which are related to poorer quality of life.

Key words: Neuropsychology, obsessive-compulsive disorder, schizophrenia, neurological disease.


This is an open access article published under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Cite this article as:

Temircan Z (2021). Comparative clinical and neuropsychological characteristics in schizophrenia and schizophrenia-obsessive compulsive disorder patients. Acad . J. Biotechnol. 9(2): 038-045.

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