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Classifications

  1. Acad. J. Med. Plant.


ajmp

Research Paper

Academia Journal of Medicinal Plants 9(12): 180-184, December 2021
DOI: 10.15413/ajmp.2021.0131
ISSN: 2315-7720
2021 Academia Publishing

Abstract


In vivo antioxidant activities of green and black grape (Vitis vinifera L.) berries against DMBA/Croton oil induced oxidative stress in mice.



Accepted 21st November, 2021

 

Meenal Sharma1* and Ritu Thakur Bais2

1Research Scholar, Department of Microbiology, Barkatullah University, Bhopal (M.P.)-462026, India
2Professor, Department of Botany, Govt. MLB Girls PG (Auto) college, Bhopal (M.P.)-462010, India

*Corresponding author. E-mail: msmeenalsharma88@gmail.com



 

Grape’s antioxidants are associated with anti-inflammatory activity which is apparently related with chemo preventive actions. Since grapes come in various colours and varieties, it becomes essential to know which one is more beneficial and what kind of benefits it accounts for. Current research was carried out for evaluating in vivo antioxidant activities of green and black grape berries (Vitis vinifera L.) against DMBA/Croton oil induced oxidative stress. The effect of methanolic green and black grapes separately and in combination was evaluated to modulate oxidative stress in swiss albino mice through lipid peroxidase test (LPO), superoxide dismutase (SOD) method and reduced glutathione (GSH) estimation. Swiss albino mice were divided into five experimental groups according to their treatment procedures. According to the result, black grape methanolic extract was potent in preventing the damage caused due to oxidative stress followed by green + black grape methanolic extract and green grape methanolic extract as compared to control group.



Key words: Vitis vinifera L., chemoprevention, in vivo test, antioxidant activity, swiss albino mice, DMBA/Croton oil, oxidative stress, green grapes, black grapes, methanolic extract, LPO, SOD, GSH.


       

This is an open access article published under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Cite this article as:
Sharma M, Bais RT (2021). In vivo antioxidant activities of green and black grape (Vitis vinifera L.) berries against DMBA/Croton oil induced oxidative stress in mice. Acad. J. Med. Plants. 9(12): 180-184.

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