In the search for novel antibacterial, the fruit peel of a medicinal plant:
Mill was investigated for activity. The study was to evaluate
the antibacterial efficacy of the crude ethanolic and aqueous extract of the
fruit peel of
Mill against selected clinical isolates. The agar
well diffusion method was used in the study. Phytochemical screening was
conducted on plants which revealed the presence of saponin, fixed oils,
carbohydrates, tannins, reducing sugars, protein, steroids, terpenoids and
phlobatannins in both extract in addition to the aforementioned phytochemicals,
anthranal glycoside was present only in the aqueous extract while alkaloids was
present in the ethanolic extract. The treatments with significant activity were
between 125 to 500 mg/ml for the antibacterial. Antibacterial disc was
incorporated to check for the sensitivity of the bacteria,
showed 50, 0 and 10% resistance respectively. The result of the
antibacterial screening revealed the sensitivity of the bacteria to ethanol
extract in this order
with mean zones of
inhibition ranging from 6 to 14, 3 to 15 and 3 to 8 mm respectively. For aqueous
S. vulgaris>E. coli
with mean zone of inhibition ranging from
0 to 15, 0 to 4 and 0 mm respectively. There was a significant difference
between the activity of the aqueous extract and ethanolic extract against these
bacteria at 95% confidence level. The general results of the evaluation
considered the plant as a very potential source of novel antibacterial agents
against Enterobacteriacea and ethanol, a better extracting solvent.
Antibacterial, fruit peel, resistance, enteric bacteria.
This is an open
access article published under the terms of the
Commons Attribution License, which permits unrestricted use,
distribution, and reproduction in any medium, provided the
original work is properly cited.
Cite this article as: Enwa FO, Michael O, Anie CO, Ayeh RA (2016).
Antibacterial Screening of the Ethanol and Aqueous Extract of the Fruit Peel of
Persea Americana Mill against Selected Enteric Bacteria. Acad. J. Microbiol.
Res. 4(3): 040-046.