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  1. Acad J Pharm Pharmacol

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ajpp

Research Article

Academia Journal of Pharmacy and Pharmacology 4(2): 036-043, June 2016
DOI: 10.15413/ajpp.2016.0436
ISSN 2315-7828
2016 Academia Publishing

Abstract

 

Yacon’s (Smallanthus Sonchifolius Poepp. and Endl.) Effects on Postprandial Glucose under Experimental Diabetes Mellitus.

 

Accepted 4th May, 2016

 

Khokhla M.1*, Horbulinska O.1, Hachkova H.1, Mishchenko L.2, Shulga O.3, Vildanova R.3 and Sybirna N.1

 

1Department of Biochemistry, Faculty of Biology, Ivan Franko National University of Lviv, Hrushevskyi Street4, Lviv 79005, Ukraine.

2Taras Shevchenko National University of Kyiv, Volodymyrska Street 64/13, Kyiv 01601, Ukraine. 3Department of Physical Chemistry of Combustible Minerals L.M. Lytvynenko Institute of Physico-organic Chemistry and Coal Chemistry NAS of Ukraine.

 

*Corresponding author e-mail: khmarija@gmail.com. Tel: +380676963530.

 

The article describes the finding of the researched yacon leaves and root tubers water extracts as well as, yacon root tubers suspensions effects on glucose tolerance in animals with experimental diabetes mellitus. It has been shown that the studied yacon extracts and suspensions at the dose of 0.5 g/kg produce significant hypoglycemic effect under the experimental diabetes mellitus. The glucose tolerance test and the analysis of the area under the glycemic curves revealed that yacon root tubers in the form of a stabilized suspension exert the best hypoglycemic effect.

 

Key words: Yacon (Smallanthus sonchifolius Poepp. and Endl.), diabetes mellitus, hypoglycemic effect.
 

This is an open access article published under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

 

Cite this article as:

Khokhla M, Horbulinska O, Hachkova H, Mishchenko L, Shulga O, Vildanova R, Sybirna N (2016). Yacon’s (Smallanthus Sonchifolius Poepp. and Endl.) Effects on Postprandial Glucose under Experimental Diabetes Mellitus. Acad. J. Pharm. Pharmacol. 4(2): 036-043.

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