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Research Article

Academia Journal of Scientific Research 7(10): 553-558, October 2019
DOI: 10.15413/ajsr.2019.0142
ISSN: 2315-7712
2019 Academia Publishing 



Eccrine carcinoma: Two cases of an unusual neoplasm and review of the literature

Accepted 30th April 2019

Clara Matas-Nadal1,3, Felip Vilardell2,3 and Rafael S. Aguayo Ortiz1,3

1Department of Dermatology. Hospital Universitari Arnau de Vilanova, Lleida, Catalonia, Spain.
2Department of Pathology, Hospital Universitari Arnau de Vilanova, Lleida, Catalonia, Spain.
3Institute of Biomedical Research of Lleida (IRBLleida), Lleida, Catalonia, Spain.

Eccrine carcinomas are clinically unspecific tumours and are often misdiagnosed by dermatologist; this is the reason whereby histological findings are keys for a correct diagnosis. Usually, these carcinomas arise as non-ulcerated nodules or plaques in the head or trunk of older patients. Regarding its behaviour, it is considered aggressive, being able to spread to lymph nodes or become a widespread metastatic disease. In this work, we report two cases of a rare malignant skin tumours derived from the eccrine sweat glands; a 23-year-old male and 34-year-old female presented with a syringoid eccrine carcinoma in the foot and a squamoid eccrine ductal carcinoma in the axilla, respectively. Due to its exceptionality, we reviewed the literature and describe all the previously reported cases in English literature, analysing the characteristics of the patients and the features of the tumours. There are very few reported cases of eccrine carcinomas with the characteristics of our patients (young age and/or located in the limbs), which means that our cases are quite exceptional. Despite the lack of consensus on management and treatment, it seems that Mohs micrographic surgery is the most appropriated treatment option and imaging studies as PET-TC should be performed for the evaluation of disseminated disease.

Key words: Eccrine carcinoma, eccrine sweet glands, non-melanoma skin cancer, squamoid eccrine ductal carcinoma, syringoid eccrine carcinoma.

This is an open access article published under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Cite this article as:

Matas-Nadal C, Felip V, Rafael SAO (2019). Eccrine carcinoma: Two cases of an unusual neoplasm and review of the literature. Acad. J. Sci. Res. 7(10): 553-558.

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