Accepted 14^th February 2020

Donmez N.¹, Keskin E.¹, Shoshin OM. A.², Ozsan M.³, and Mehtap B.<sup>4

1</sup>University of Selcuk, Faculty of Veterinary, Department of Physiology, 42075, Konya, TURKEY
² Kirkuk University, Collage of Veterinary, IRAQ.
³University of Bartın, Faculty of Education, Bartın, TURKEY.
⁴University of Selcuk, Faculty of Sport Sciences, Konya, TURKEY.


 Diabetes Mellitus is the most common endocrine disorder in the growing world. A heterogeneous group that is related to different causes and causes different complications can be defined as a complicated metabolic disorder. It is known that exercise has beneficial effects in the prevention and/or reducing of pathologies associated with diabetes. The aim of this study was to evaluate the effects of regular swimming training on some hematological parameters in type-1 diabetic rats. Thirty-two adult male Wistar albino rats were divided into four equal groups as Control (C), Diabetes (D), Exercise Control (E) and Diabetes+Exercise (DE). All groups were fed with standart rat food during the experiment. The rats in the control group did not receive any treatment, while the D and DE groups were injected ip 60 mg / kg STZ intraperitoneally. The trial continued for four weeks after the onset of diabetes. After the diabetes was formed, 1 hour swimming exercise for 4 weeks, 5 days a week was applied to groups E and DE during the trial period. In blood samples, leukocyte (WBC), erythrocyte (RBC), hemoglobin (HGB), hematocrit (HCT), platelet (PLT) and differential leucocyte count were examined. RBCs, Hb and HTC values were reduced in D group. On the other hand, WBC and platelet count were increased in the same group. We observed RBC count, Hb and Htc levels were higher and WBC count was lower in DE group according to D group. As a result, the present study was observed that regular aerobic exercise improves investigated parameters and demonstrates positive effects.

Key words: Diabetes mellitus, exercise, hematological parameters, rat, swimming.