Acute oral toxicity of MethanolicExtract
ofPandanusodorattissimusleaves in Albino Mice as per
OECD 425 TG
Accepted 19th
March, 2022
Abhaykumar Kamble and Paramjyothi Swamy*
Department of Biochemistry, Gulbarga University,
Kalaburagi, India.
Anticancer activity of Methanolic Extract of
Pandanusodoratissimus (MEPO)was studied against
Ehrlich Ascites Carcinoma (EAC) cells in Swiss
albino mice. Anticancer activity of MEPO was
examined by determining the body weight, average
tumor weight, tumor cell volume, cell count,
viable, mean survival time, life span and
hematological parameter. The crude extract
increased the life span of EAC treated mice and
restored the hematological parameters. Thus, the
present study reveals anticancer potential of
MEPO against EAC in experimental models.
This is an open access article
published under the terms of the
Creative Commons Attribution
License, which permits unrestricted use, distribution, and
reproduction in any medium, provided the original work is
properly cited.
Cite this article as:
Kamble A, Swamy P (2022).
Acute oral toxicity of MethanolicExtract ofPandanusodorattissimusleaves in
Albino Mice as per OECD 425 TG. Acad. J. Sci.
Res. 10(5): 078-085.