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Research Article

Academia Journal of Scientific Research 10(5): 078-085, May 2022
DOI: 10.15413/ajsr.2022.0104
ISSN 2315-7712
2022 Academia Publishing

Abstract


Acute oral toxicity of MethanolicExtract ofPandanusodorattissimusleaves in Albino Mice as per OECD 425 TG

 

Accepted 19th March, 2022
 

Abhaykumar Kamble and Paramjyothi Swamy*

Department of Biochemistry, Gulbarga University, Kalaburagi, India.
 


Anticancer activity of Methanolic Extract of Pandanusodoratissimus (MEPO)was studied against Ehrlich Ascites Carcinoma (EAC) cells in Swiss albino mice. Anticancer activity of MEPO was examined by determining the body weight, average tumor weight, tumor cell volume, cell count, viable, mean survival time, life span and hematological parameter. The crude extract increased the life span of EAC treated mice and restored the hematological parameters. Thus, the present study reveals anticancer potential of MEPO against EAC in experimental models.


Key words: Pandanusodoratissimus, crude extract, anticanceractivity, EAC cell, Vinblastine.
 

This is an open access article published under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Cite this article as:

Kamble A, Swamy P  (2022). Acute oral toxicity of MethanolicExtract ofPandanusodorattissimusleaves in Albino Mice as per OECD 425 TG. Acad. J. Sci. Res. 10(5): 078-085.

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